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Comparative Effectiveness of 10 Antiepileptic Drugs in Older Adults With Epilepsy Arch Neurol 67:408-415, Arif,H., et al, 2010 See this aricle in Pubmed Article Abstract In this study of older adults with epilepsy, lamotrigine was the most effective AED as measured by 12-month retention and seizure freedom, with levetiracetam a close second. Oxcarbazepine was consistently less effective than most other AEDs.

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