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Spatial Relation Between Microbleeds and Amyloid Deposits in Amyloid Angiopathy
Ann Neurol 68:545-548, Dierkson,G.A.,et al, 2010
See this aricle in Pubmed
Article Abstract
On coregistered positron emission tomography (PET) and MRI images, PiB retention was increased at microbleed sites compared to simulated control lesions (p = 0.002) and declined with increasing distance from the microbleed (p < 0.0001). These findings indicate that microbleeds occur preferentially in local regions of concentrated amyloid and support therapeutic strategies aimed at reducing vascular amyloid deposition.
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amyloid angiopathy,cerebral
microhemorrhage,intracerebral
MRI,gradient-echo
Pittsburgh Compound B
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