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Risk of Recurrence After a First Seizure and Implications for Driving: Further Analysis of the Multicentre Study of Early Epilepsy and Single Seizures BMJ 341:c6477, 1227, Bonnet,L.J.,et al, 2010 See this aricle in Pubmed Article Abstract After a single unprovoked seizure this reanalysis of MESS provides estimates of seizure recurrence risks that will inform policy and guidance about regaining an ordinary driving license. Further guidance is needed as to how such data should be utilized; in particular, whether a population approach should be taken with a focus on the unadjusted results or whether attempts should be made to individualise risk. Guidance is also required as to whether the focus should be on risk estimates only or on the confidence interval as well. If the focus is on the estimate only our unadjusted estimates suggest that treated and untreated patients are eligible to drive after being seizure-free for six months. If the focus is also on confidence intervals, direction is needed as to whether a conservative or liberal approach should be taken.

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