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Brain Biopsy in Children With Primary Small-Vessel Central Nervous System Vasculitis
Ann Neurol 68:602-610, 573, Elbers,J.,et al, 2010
See this aricle in Pubmed

Article Abstract
In children presenting with new onset severe headaches, seizures, or cognitive decline, SVcPACNS and brain biopsy should be considered. Lesional biopsies are preferred; however, nonlesional biopsies may succeed in yielding the diagnosis. Steroid treatment prior to biopsy and inadequate biopsy sampling may obscure the diagnosis in true cases of SVcPACNS.
 
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angiitis,isolated of CNS
angiography,cerebral
angiography,cerebral,false negative
brain biopsy
cerebrospinal fluid,elevated protein of
children
cognition
C-reactive protein,elevated
dementia
dementia,childhood
headache
immunosuppressive agents
meningeal enhancement
MRI,abnormal
MRI,contrast enhanced
negative
neurologic disease,diagnoses of
optic neuritis
optic neuritis,bilateral
pleocytosis of cerebrospinal fluid
sedimentation rate,elevated
seizure
small vessel disease
status epilepticus
status epilepticus,intractable
steroid therapy,CNS treatment and complications with
treatment of neurologic disorder
visual loss

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