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HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans
NEJM 364:1126-1133, Chen,P.,et al, 2011
See this aricle in Pubmed
Article Abstract
The identification of subjects carrying the HLA-B*1502 allele and the avoidance of carbamazepine therapy in these subjects was strongly associated with a decrease in the incidence of carbamazepine-induced SJS-TEN.
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adverse drug reaction
anticonvulsants,hypersensitivity syndrome
anticonvulsants,untoward effects of
carbamazepine
carbamazepine,toxicity
complications
HLA
hypersensitivity reaction
iatrogenic neurologic disorders
risk factors
skin,lesions in neurologic disorders
southeast asia
Stevens-Johnson syndrome
Taiwan
toxic epidermal necrolysis
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