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Acute Hepatic Encephalopathy with Diffuse Cortical Lesions
Neuroradiology 43:551-554, Arnold, S.M.,et al, 2001
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Article Abstract
Acute hepatic encephalopathy is a poorly defined syndrome of heterogeneous aetiology. We report a 49-year-old woman with alcoholic cirrhosis and hereditary haemorrhagic telangiectasia who developed acute hepatic coma induced by severe gastrointestinal bleeding. Laboratory analysis revealed excessively elevated blood ammonia. MRI showed lesions compatible with chronic hepatic encephalopathy and widespread cortical signal change sparing the perirolandic and occipital cortex. The cortical lesions resembled those of hypoxic brain damage and were interpreted as acute toxic cortical laminar necrosis.
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alcoholism
ammonia
cerebral cortex
cerebral edema
cirrhosis
coma
deep gray nuclei
hepatic encephalopathy
hepatic encephalopathy, acute
hepatic failure
laminar necrosis,cortical
liver disease
liver function enzymes
MRI
MRI,abnormal
MRI,diffusion weighted
neurotoxin
symmetric brain lesions
thalamus,lesion of
thalamus,lesion of-bilateral
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