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Risk of Natalizumab-Associated Progressive Multifocal Leukoencephalopathy
NEJM 366:1870-1880,1938, Bloomgren, G.,et al, 2012
See this aricle in Pubmed

Article Abstract
Positive status with respect to anti-JC virus antibodies, prior use to immunosuppressants, and increased duration of natalizumab treatment, alone or in combination, were associated with distinct levels of PML risk in natalizumab-treated patients with multiple sclerosis.
 
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algorithm
anti JC virus antibodies
complications
iatrogenic neurologic disorders
immunosuppression
immunosuppressive agents
JC virus
monoclonal antibodies
multiple sclerosis
multiple sclerosis,treatment of
natalizumab
progressive multifocal leucoencephalopathy
risk factors
safety
serologic testing
treatment of neurologic disorder

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