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The Benefits and Harms of Intravenous Thrombolysis with Recombinant Tissue Plasminogen Activator within 6 h of Acute Ischaemic Stroke (the third international stroke trial IST-3): a Randomised Controlled Trial
Lancet 379: 2320, IST-3 collaborative group, 2012
See this aricle in Pubmed
Article Abstract
For the types of patient recruited in IST-3, despite the early hazards, thrombolysis within 6 h improved functional outcome. Benefit did not seem to be diminished in elderly patients.
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cerebrovascular accident
cerebrovascular accident,thrombolytic agents in treatment
efficacy
fibrinolytic agents
fibrinolytic therapy,timing of administration
prognosis
safety
tissue plasminogen activator,intravenous
treatment of neurologic disorder
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