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Herpes Simplex Encephalitis during Treatment with Tumor Necrosis Factor- Inhibitors
CID 49:924-927, Bradford, R.D.,et al, 2009
See this aricle in Pubmed

Article Abstract
We report 3 cases of herpes simplex virus encephalitis in patients receiving tumor necrosis factor-alpha (TNF-) inhibitors for rheumatologic disorders. Although TNF- inhibitors have been reported to increase the risk of other infectious diseases, to our knowledge, an association between anti-TNF- drugs and herpes simplex virus encephalitis has not been previously described.
 
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acyclovir
adalimumab
adverse drug reaction
atypical
central nervous system,infection of
complications
encephalitis
encephalitis,viral
fever
headache
herpes simplex encephalitis
herpes simplex encephalitis,atypical
herpes simplex virus infection,immunosuppressed patient
immunosuppression
infection
infliximab
monoclonal antibodies
MRI,abnormal
MRI,false negative
MRI,negative
opportunistic infection
opportunistic infection,CNS
pleocytosis of cerebrospinal fluid
polymerase chain reaction
polymerase chain reaction,false negative
psoriatic arthritis
rheumatoid arthritis
temporal lobe,lesion
temporal lobe,lesion,bilateral
treatment of neurologic disorder
tumor necrosis factor inhibitor
viral infection

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