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Adult-Onset Subacute Sclerosing Panecephalitis:Case Reports and Review of the Literature Mov Dis 12:342-353, Singer,C.,et al, 1997 See this aricle in Pubmed Article Abstract Subacute sclerosing panencephalitis (SSPE) is mainly thought of as a disorder of childhood and adolesence and may not be readily recognized when presenting later in life. Prior reports have suggested that adult-onset SSPE may have atypical features. We have added two cases to the existing literature on adult-onset SSPE, compared them with a more classic juvenile presentsatation, and extensively reviewed those reports that were published after the etiological link with the measles virus has been established. The importance of recognizing the spectrum of potential presentations of SSPE and providing an early diagnosis will increase as more efffective treatments become available.

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