Neurology Specific Literature Search   
 
[home][thesaurus]
    
Click Here to return To Results

 

Value of MRI of the Brain in Patients with Systemic Lupus Erythematosus and Neurologic Disturbance
Neuroradiol 46:15-21, Jennings, J.E.,et al, 2014
See this aricle in Pubmed

Article Abstract
We reviewed 116 MRI examinations of the brain performed on 85 patients with SLE, (81 women, four men, aged 21-78 years, mean 40.6 years) presenting with neurological disturbances. MRI was normal or nearly normal in 34%. In 60% high-signal lesions were observed on T2-weighted images, frequently in the frontal and parietal subcortical white matter. Infarct-like lesions involving gray and white matter were demonstrated in 21 of cases. Areas of restricted diffusion were seen in 12 of the 67 patients who underwent diffusion-weighted imaging. Other abnormalities included loss of brain volume, hemorrhage, meningeal enhancement, and bilateral high signal in occipital white-matter. The MRI findings alone did not allow us to distinguish between thromboembolic and inflammatory events in many patients. Some patients with normal MRI improved clinically while on immunosuppressive therapy. More sensitive and/or specific imaging methods, such as spectroscopy and perfusion-weighted imaging, should be investigated in these subgroups of patients with suspected NP-SLE.
 
Related Tags
(click to filter results - removes previous filter)

ANA
antiphospholipid antibodies
antiphospholipid antibody syndrome
cerebrovascular accident
confusion
confusional state,acute
gray matter
gyral hemorrhage
gyrus,abnormal
headache
meningeal enhancement
MRI,abnormal
MRI,contrast enhanced
MRI,diffusion weighted
MRI,negative
MRI,serial
small vessel disease
systemic lupus erythematosus
systemic lupus erythematosus,neurologic complications with
vasculopathy
white matter disease

Click Here to return To Results