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Rarely, however, it may progress to a chronic state, and more rarely still to a granulomatous encephalitis. Prior studies have suggested that antiviral immunity with Toll-like receptors determines susceptibility to herpes viruses. The authors report the case of a 14-year-old girl with a remote history of treated HSV encephalitis, who had intractable seizures and worsening MR imaging changes that were concerning for either a neoplastic or an inflammatory process. She was found to have granulomatous herpes simplex encephalitis and had a low cytokine response to Toll-like receptor 3 stimulation. |
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calcification,intracranial children encephalitis granulomatous disease herpes encephalitis herpes simplex encephalitis herpes simplex encephalitis,atypical herpes simplex encephalitis,chronic herpes simplex encephalitis,extra temporal herpes simplex encephalitis,infancy and childhood herpes simplex encephalitis,recurrent MRI,abnormal MRI,contrast enhanced neuropathology polymerase chain reaction
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