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Reversible Posterior Leukoencephalopathy Syndrome in 2 HIV-Infected Patients Receiving Antiretroviral Therapy
CID 49:e19-e22, Ridolfo, A.L.,et al, 2008
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Article Abstract
We describe 2 human immunodeficiency virus-infected patients who developed hypertension and severe neurological abnormalities while receiving successful antiretroviral therapy. Neuroimaging findings were characteristic of reversible posterior leukoencephalopathy syndrome, a brain-capillary leak syndrome with hypertension and endothelial damage. We discuss the role of antiretroviral therapy-associated metabolic alterations in endothelial damage, hypertension, and reversible posterior leukoencephalopathy syndrome.
 
Related Tags
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acquired immunodeficiency syndrome
adverse drug reaction
antiviral agents
complications
human immunodeficiency virus type 1
hypertension
MRI,abnormal
posterior leukoencephalopathy syndrome
reversible cerebral vasoconstrictive syndromes

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