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A Case of Statin-Associated Autoimmune Myopathy
Clin Med Insights: Case Reports 10:1-4, Sweidan, A.J.,et al, 2017
See this aricle in Pubmed

Article Abstract
Statin-associated autoimmune myopathy is a very rare complication of statin use and estimated to affect two or three for every 100,000 patients treated. Clinically, the condition presents as progressive symmetric weakness, muscle enzyme elevations, necrotizing myopathy on muscle biopsy, and the presence of autoantibodies to HMGCR. These findings will often persist and even progress despite discontinuation of the statin. Very few cases of SAM have been described in the literature. Describing this rare condition and the ultimately fatal outcome of our patient, we aim to further understanding of SAM, its presentation and clinical course to promote earlier diagnosis and prompt management.
 
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autoantibodies
complications
creatine phosphokinase(CPK)elevated
drug induced neurologic disorders
HMGcoA reductase inhibitors
iatrogenic neurologic disorders
myopathy
myopathy,drug-induced
myopathy,necrotizing,autoimmune
progressive neurologic disorder
respiratory failure
statin therapy
weakness
weakness,generalized
weakness,progressive

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