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Natural History of "Pure" Primary Lateral Sclerosis
Neurol 96:e2231-e2238, Hassan, A.,et al, 2021
See this aricle in Pubmed

Article Abstract
Pure PLS did not convert to ALS after a median of 9 years disease duration follow-up in our study population. The ascending paraparetic phenotype was most common, with earlier onset and frequent bladder involvement. After years of pure PLS, <5% develop a more pervasive neurodegenerative disorder.
 
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amyotrophic lateral sclerosis
electromyogram
motor neuron disease
primary lateral sclerosis
prognosis

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