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Effect of Intra-Arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients with Large Vessel Occlusion Acute Ischemic Stroke
JAMA 327:826-835,821, Renu, A.,et al, 2022
See this aricle in Pubmed

Article Abstract
Among patients with large vessel occlusion acute ischemic stroke and successful reperfusion following thrombectomy, the use of adjunct intra-arterial alteplase compared with placebo resulted in a greater likelihood of excellent neurological outcome at 90 days. However, because of study limitations, these findings should be interpreted as preliminary and require replication.
 
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cerebrovascular accident
cerebrovascular accident,surgical treatment of
CHOICE trial
endovascular therapy
fibrinolytic agents,intra-arterial local infusion
middle cerebral artery,occlusion of
prognosis
reperfusion
review article
thrombectomy
treatment of neurologic disorder

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