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In 434 operations for valvular heart disease,patients were randomised to receive Bjork-Shiley,Edwards-Duromedics,or Medtronic-Hall mechanical prostheses.At a median follow-up time of 37.5 months there were no differences in hazard of death or non-embolic events.In the first six postoperative months the incidence of thromboembolism was about the same for the three valves.Subsequently,however,the incidence of thromboembolism for the Edwards-Duromedics valve was 3.9 times higher than for the Bjork- Shiley valve,and for the Medtronic-Hall valve 2.6 times higher than for the Bjork-Shiley valve. |
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