|
|
|
|
|
Click Here to return To Results
|
|
|
|
Chronic alcoholics may have CNS lesions,such as microvasculitis or glial, neural,and myelin degeneration,as documented in postmortem studies on subjects who had Wernicke encephalopathy,corpus callosum degeneration,or central pontine myelinolysis.One may also expect the presence of early white matter disease in patients who do not have neurologic complications of alcoholism.Thirty-five chronic alcoholics(Diagnostic and Statistical manual III criteria)and 35 normal control subjects were studied by means of magnetic resonance(MR)imaging.Subjects>60 years old,or those with CNS involvement,or clinically evident systemic disorders were excluded.Of the remaining asymptomatic alcoholics,MR detected multiple round hyperintense areas in the white matter of 14 patients,in addition to aspecific corticosubcortical and cerebellar atrophies.None of the normal control subjects showed such a finding.These results suggest an early involvement of the brain in asymptomatic alcoholic patients. |
|
(click to filter results - removes previous filter)
alcohol
alcohol,neurologic complications with
alcoholism
MRI
MRI,abnormal
white matter disease
white matter disease,periventricular
|
Click Here to return To Results
|
|