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Isolation of Herpes Simplex Virus Type 1 During First Attack of Multiple Sclerosis Ann Neurol 26:283-285, Bergstrom,T.,et al, 1989 See this aricle in Pubmed Article Abstract Herpes simplex virus type 1 was isolated from the cerebrospinal fluid of a patient during the first attack of multiple sclerosis.This is the first virus to be isolated from the central nervous system of a living patient with MS.The virus was identified as herpes simplex virus type 1 by restriction endonuclease analysis and by an enzyme immunoassay using monoclonal antibodies.Antibodies against type 1 but not type 2 were detected in consecutive samples of serum and cerebrospinal fluid.The patient has since entered a progressive phase of multiple sclerosis.The isolated type 1 strain might be of pathogenetic relevance to the development of multiple sclerosis in this patient.

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(click to filter results - removes previous filter) cerebrospinal fluid cerebrospinal fluid,culture of,viral herpes simplex virus multiple sclerosis viral infection viral infection,CNS viral isolation

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