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We randomly assigned dexamethasone in an initial bolus of 10 mg IV or 100 mg IV followed by 16 mg daily orally to 37 patients with metastatic spinal cord compression.The average pain score before the start of treatment was 5.2(SD=2.8)and decreased significantly(p<0.001)to 3.8 at 3 hrs,2.8 at 24 hrs,and 1.4 after 1 week.There were no differences between the conventional and high-dose group on pain,ambulation,or bladder function. |
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spinal cord,compression of
spinal cord,metastasis to
spinal cord,metastasis to,treatment of
spine,metastasis to
steroid
steroid therapy,CNS treatment and complications with
treatment of neurologic disorder
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