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Cortical Blindness Due to Osmotic Disruption of the Blood-Brain Barrier by Angiographic Contrast Material:CT and MRI Studies Neurol 39:567-571, Lantos,G., 1989 See this aricle in Pubmed Article Abstract Numerous experimental studies have demonstrated disruption of the blood- brain barrier by the hyperosmolar,iodinated contrast agents in common use for intravascular injection during radiologic studies.We report 4 cases in which cortical blindness occurred after cerebral angiography.The patients underwent x-ray CT within 1 hour.CT showed abnormal contrast enhancement in the occipital regions in all 4 instances.Two patients underwent MRI;1 of these manifested abnormal high-signal intensity in the occipital lobes on T2-weighted images.Only 2 previous cases documenting immediate contrast enhancement within the brain substance on CT following angiography are in the literature.

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(click to filter results - removes previous filter) angiography,cerebral angiography,neurologic complications with blood brain barrier CAT scan CAT scan,abnormal CAT scan,contrast enhanced contrast agents,neurotoxicity of cortical blindness iatrogenic neurologic disorders MRI MRI,abnormal

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