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A Case of Subacute Combined Degeneration:MRI Findings
Neuroradiology 40:398-400, Yamada,K.,et al, 1998
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Article Abstract
The specific spinal cord lesion caused by vitamin B12 deficiency is known as subacute combined degeneration(SCD).Neuropathological studies of SCD show lesions mainly in the posterior and lateral columns involving the corticospinal and spinocerebellar tracts.We report a case of SCD in a 19 year old man who presented with 4 weeks history of gradually progressing tingling in both hands.MRI of the cervical spine demonstrated symmetrical areas of T2 signal abnormality involving the dorsal columns of the cervical cord from the C2 through C5 levels associated with spinal cord expansion.He was treated with vitamin B12 supplements and experienced gradual improvement in his clinical symptoms.Repeat MRI of the cervical spine after 2 months revealed slight decrease in the area of abnormal signal.
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B 12 deficiency
MRI,spinal cord
pernicious anemia
posterior column disease
spinal cord
spinal cord,lesion of

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