Intravenous Alteplase for Stroke: Beyond the Guidelines and in Particular Clinical Situations
Stroke 38:2612-2618, De Keyser,J.,et al, 2007
Small Step or Giant Leap? Expanding the Acute Stroke Thrombolysis Window to 24 Hour
NEJM 391:273-275, Lee,V.H., 2024
Melbourne Mobile Stroke Unit and Reperfusion Therapy
Stroke 51:922-930, Zhao, H.,et al, 2020
Machine Learning Approach to Identify Stroke Within 4.5 Hours
Stroke 51:860-866, Lee, H.,et al, 2020
Thrombolysis for Acute Ischemic Stroke in the Unwitnessed or Extended Therapeutic Time Window
Neurol 94:e1241-e1248, Tsivgoulis, G.,et al, 2020
Implementation of a Prehospital Stroke Triage System Using Symptom Severity and Teleconsultation in the Stockholm Stroke Triage Study
JAMA Neurol 77:691-699, Mazya, M.V.,et al, 2020
Lesion Age Imaging in Acute Stroke: Water Uptake in CT Versus DWI-FLAIR Mismatch
Ann Neurol 88:1144-1152, Broocks, G.,et al, 2020
Penumbra Detection in Acute Stroke with Perfusion Magnetic Resonance Imaging: Validation with 15 O-Positron Emission Tomography
Ann Neurol 85:875-886, Zaro-Weber, O.,et al, 2019
Automated DWI analysis can identify patients within the thrombolysis time window of 4.5 hours
Neurol 90:e1570-e1577, Wouters, A.,et al, 2018
Time to Decision and Treatment with tPA (Tissue-Type Plasminogen Activator) Using Telemedicine Versus an Onboard Neurologist on a Mobile Stroke Unit
Stroke 49:1528-1530, Bowry, R.,et al, 2018
Intravenous Thrombolysis in Unwitnessed Stroke Onset: MR WITNESS Trial Results
Ann Neurol 83:980-993, Schwamm, L.H.,et al, 2018
Reduction in Time to Treatment in Prehospital Telemedicine Evaluation and Thrombolysis
Neurol 88:1305-1312, Taqui, A.,et al, 2017
And Why Not Thrombolysis in the Ambulance (At Least for Some)?
Neurol 87:214-219, Rosenberg, G. & Steiner, I., 2016
Implementing a Mobile Stroke Unit Program in the United States
JAMA Neurol 72:229-234, Rajan, S.,et al, 2015
Effects of Golden Hour Thrombolysis
JAMA Neurol 72:25-30,9, Ebinger, M.,et al, 2015
Screening with MRI for Accurate and Rapid Stroke Treatment
Neurol 84:2438-2444, 2394, Shah, S.,et al, 2015
Prehospital Thrombolysis in Acute Stroke
Neurol 80:163-168, Weber, J.,et al, 2013
Endovascular Treatment for Acute Ischemic Stroke-Still Unproven
NEJM 368:952-955, Chimowitz,M., 2013
Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke
NEJM 368:893-903,952, Broderick, J.P.,et al, 2013
Results of Intravenous Thrombolysis within 4.5 to 6 Hours and Updated Results within 3 to 4.5 Hours of Onset of Acute Ischemic Stroke Recorded in the Safe Implementation of Treatment in Stroke International Stroke Thrombolysis Register (SITS-ISTR)
JAMA Neurol 70:837-844, Ahmed, N.,et al, 2013
A Case-Controlled Comparison of Thrombolysis Outcomes Between Wake-Up and Known Time of Onset Ischemic Stroke Patients
Stroke 44:2226-2231, Manawadu, D.,et al, 2013
Thrombolysis of Basilar Artery Occlusion: Impact of Baseline Ischemia and Time
Ann Neurol 73:688-694, Strbian, D.,et al, 2013
The Benefits and Harms of Intravenous Thrombolysis with Recombinant Tissue Plasminogen Activator within 6 h of Acute Ischaemic Stroke (the third international stroke trial IST-3): a Randomised Controlled Trial
Lancet 379: 2320, IST-3 collaborative group, 2012
Recombinant Tissue Plasminogen Activator for Acute Ischaemic Stroke: An Updated Systematic Review and Meta-Analysis
Lancet 379: 2364-2372, Wardlaw, J.M.,et al, 2012
A Pragmatic Approach Using Magnetic Resonance Imaging to Treat Ischemic Strokes of Unknown Onset Time in a Thrombolytic Trial
Stroke 43:2331-2335, Song, S.S.,et al, 2012
Helicopter Transport of Stroke Patients and Its Influence on Thrombolysis Rates
Stroke 42:1295-1300, Reiner-Deitemyer, V.,et al, 2011
Effects of Extending the Time Window of Thrombolysis to 4.5 Hours Observations in the Swedish Stroke Register (Riks-Stroke)
Stroke 42:2492-2497, Asplund, K.,et al, 2011
Remote Supervision of IV-tPA for Acute Ischemic Stroke by Telemedicine or Telephone Before Transfer to a Regional Stroke Center Is Feasible and Safe
Stroke 41:e18-e24, Pervez,M.,et al, 2010
Fluid-Attenuated Inversion Recovery Evolution Within 12 Hours from Stroke Onset: A Reliable Tissue Clock?
Stroke 41:250-255, 197, Ebinger,M.,et al, 2010
Endovascular Treatment of Acute Ischemic Stroke May Be Safely Performed With No Time Window Limit in Appropriately Selected Patients
Stroke 41:1996-2000, Abou-Chebl,A.,et al, 2010
Use of MRI to Estimate the Therapeutic Window in Acute Stroke: Is Perfusion-Weighted Imaging/Diffusion-Weighted Imaging Mismatch an EPITHET for Salvageable Ischemic Brain Tissue?
Stroke 40:333-335, Toth,G. &Albers,G.W., 2009
Expansion of the Time Window for Treatment of Acute Ischemic Stroke with Intravenous Tissue Plasminogen Activator: A Science Advisory from the American Heart Association/American Stroke Association
Stroke 40:2945-2948, del Zoppo,G.J.,et al, 2009
Number Needed to Treat to Benefit and to Harm for Intravenous Tissue Plasminogen Activator Therapy in the 3- to 4.5-Hour Window: Joint Outcome Table Analysis of the ECASS 3 Trial
Stroke 40:2433-2437,2295, Saver,J.L.,et al, 2009
Stroke Therapy Academic Industry Roundtable (STAIR) Recommendations for Extended Window Acute Stroke Therapy Trials
Stroke 40:2594-2600, Saver,J.L.,et al, 2009
MR Imaging-Based Decision in Thrombolytic Therapy for Stroke on Awakening: Report of 2 Cases
AJRN 29:1314-1316, Iosif,C.,et al., 2008
Thrombolysis with Alteplase 3-4.5 h After Ischaemic Stroke (SITS-ISTR): An Observational Study
Lancet 372:1303-1309, Wahlgren,N.,et al, 2008
Thrombolysis with Alteplase 3 to 4.5 Hours After Acute Ischemic Stroke
NEJM 359:1317-1329,1393, Hacke,W.,et al, 2008
Asymptomatic Hemorrhage After Thrombolysis May Not Be Benign: Prognosis by Hemorrhage Type in the Canadian Alteplase for Stroke Effectiveness Study Registry
Stroke 38:7579, Dzialowski,I.,et al, 2007
Comparison of CT Perfusion and Angiography and MRI in Selecting Stroke Patients for Acute Treatment
Neurol 68:694-697, Wintermark,M.,et al, 2007
MRI-Based and CT-Based Thrombolytic Therapy in Acute Stroke Within and Beyond Established Time Windows
Stroke 38:2640-2645, Schellinger,P.D.,et al, 2007
Population-Based Analysis of the Impact of Expanding the Time Window for Acute Stroke Treatment
Stroke 38:3213-3217, Juhl,J.,et al, 2007
Outcome and Symptomatic Bleeding Complications of Intravenous Thrombolysis Within 6 Hours in MRI-Selected Stroke Patients
Stroke 37:852-858, Thomalla,G.,et al, 2006
Imaging-Guided Acute Ischemic Stroke Therapy: From "Time is Brain" to "Physiology is Brain"
AJNR 27:728-735, Gonzalez,R.G., 2006
Is Penumbral Imaging Useful for Extending the Treatment Window for Intravenous Tissue Plasminogen Activator?
Ann Neurol 60:499-501, Fisher,M., 2006
Predicting Abnormal Coagulation in Ischemic Stroke: Reducing Delay in rt-PA Use
Neurol 67:1665-1667, Gottesman,R.F.,et al, 2006
Houston Paramedic and Emergency Stroke Treatment and Outcomes Study (HoPSTO)
Stroke 36:1512-1518, Wojner-Alexandrov,A.,et al, 2005
Perfusion Computed Tomography: Prediction of Final Infarct Extent and Stroke Outcome
Ann Neurol 58:672-679,661, Parsons,M.W.,et al, 2005
The Desmoteplase in Acute Ischemic Stroke Trial (DIAS): A Phase II MRI-Based 9-Hour Window Acute Stroke Thrombolysis Trial With Intravenous Desmoteplase
Stroke 36:66-73, Hacke,W.,et al, 2005
Association of Outcome with Early Stroke Treatment:Pooled Analysis of ATLANTIS, ECASS, and NINDS rt-PA Stroke Trials
Lancet 363:768-774, The ATLANTIS,ECASS,and NINDS rt-PA Study Group, 2004