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A patient who had always lived in the United States had an HTLV-I infection and a chronic myelopathy clinically mimicking amyotrophic lateral sclerosis.Needle EMG and nerve conduction studies were consistent with anterior horn cell disease but muscle biopsy showed denervation and an inflammatory myopathy.Serum HTLV-I antibody tests were positive and HTLV-I DNA was present in peripheral leukocytes.This is the 1st reported US native with HTLV-I-associated myelopathy and polymyositis. |
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