|
|
|
Click Here to return To Results
|
|
We evaluated 14 consecutive patients with leptomeningeal metastasis prospectively,using both T1-weighted(T1W)gadolinium-DTPA-enhanced MR(Gd- MR)and contrast-enhanced CT(CE-CT).Thirteen had positive CSF cytology;the remaining patient had an atypical CSF lymphocytosis and primary CNS lymphoma.The patients(8M/6F)ranged in age from 8 to 70 years(median,42 years).Tumor histology included 3 systemic and 2 primary CNS lymphomas,3 breast carcinomas,2 leukemias,1 malignant schwannoma,1 small cell lung cancer,1 prostate cancer,and 1 melanoma.Both imaging methods demonstrated parenchymal volume loss equally well in all patients.Gd-MR revealed abnormal enhancement of meninges or parenchyma in 10 patients,including all 5 patients with positive CE-CT.Neither technique revealed any foci of abnormal enhancement in 4 patients.Gd-MR was superior to CE-CT in demonstrating and quantifying enhancing subarachnoid and parenchymal nodules in 6 patients and in demonstrating sulcal,dural,cisternal, tentorial,and ependymal enhancement.Our findings indicate that T1W Gd-MR is the preferred imaging modality in leptomeningeal metastasis and suggest that CE-CT is unnecessary. |
|
(click to filter results - removes previous filter)
CAT scan CAT scan,abnormal CAT scan,contrast enhanced cerebrospinal fluid,cytology gadolinium lymphoma involving CNS meningeal enhancement meninges meningitis,carcinomatous meningitis,leukemic meningitis,lymphomatous MRI MRI,abnormal MRI,CAT scan compared to MRI,contrast enhanced neoplasm,metastatic to Dura
|
Click Here to return To Results
|
|