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To determine the diagnostic accuracy of iofetamine hydrochloride I 123 (IMP)with single photon emission computed tomography in Alzheimer's disease,we studied 58 patients with AD and 15 age-matched healthy control subjects.We used a qualitative method to assess regional IMP uptake in the entire brain and to rate image data sets as normal or abnormal without knowledge of subjects'clinical classification.The sensitivity and specificity of IMP with single photon emission computed tomography in AD were 88%and 87%,respectively.In 15 patients with mild cognitive deficits (Blessed Dementia Scale score, |
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