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78%of the demented patients and 28%of nondemented patients had a delay in latency of at least one of the evoked potential components beyond the upper limit of our normal population.By contrast,the EEG was normal in all patients with asymptomatic HIV infection and most symptomatic patients, although 5 patients in this latter group had mild generalized slowing.MRI and CT findings were similarly nonspecific,particularly in the nondemented group.Our findings suggest that long latency auditory evoked potentials may be particularly useful in the evaluation of HIV-infected patients, possibly permitting the early recognition of HIV encephalopathy and identifying those patients with a worse prognosis or in need of more aggressive management;perhaps,also,recording these potentials will permit the course of this disorder,and its response to therapy,to be followed. |
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