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A previously healthy 5-year-old boy developed cerebral vasculopathy, presenting as two episodes of acute hemiparesis 3 and 9 months, respectively,after a primary varicella infection(chickenpox).This association has not been reported before,to our knowledge,although cerebral vasculopathy is a well-known complication of herpes zoster ophthalmicus.The diagnosis was based on the presence of oligoclonal varicella-specific IgG in the cerebrospinal fluid and angiographic findings.Clinical and angiographic follow-up,and serial thymidine kinase activity levels in the cerebrospinal fluid suggested a self-limiting course of the virus-induced vasculopathy.Varicella zoster virus seems to be another potential causative agent to be considered in acute childhood hemiplegia. |
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