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Four patients with leptomeningeal metastases documented by neuroradiological examinations are reported.All had central nervous system or systemic neoplasms and showed clinical signs of carcinomatous meningitis.Gadolinium-enhanced MRI(Gd-MRI)disclosed for each patient pathological foci,allowing delineation of the extent of meningeal disease. Although non-specific,these findings,combined with the clinical context and CSF analysis,may lead to a rapid diagnosis and treatment of carcinomatous meningitis,even when malignant cells are not detected in the cerebrospinal fluid. |
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cerebrospinal fluid cerebrospinal fluid,cytology cerebrospinal fluid,cytology,false negative gadolinium meningeal enhancement meningitis,carcinomatous MRI MRI,abnormal MRI,CAT scan compared to MRI,contrast enhanced
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