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Risk of Seizure Recurrence Following a First Unprovoked Seizure in Childhood
Pediatrics 85:1076-1085, Shinnar,S.,et al, 1990
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Article Abstract
The cumulative risk of recurrence in the 81 children with abnormal electroencephalograms was 41%,54%,and 56%at 12,24,and 36 months, respectively,but only 15%,23%and 26%at 12,24,and 36 months,respectively,in the 138 children with normal electroencephalograms(p<.001).A history of epilepsy in a first-degree relative was a significant risk factor only in idiopathic cases with abnormal electroencephalograms.In children with a remote symptomatic first seizure,either a history of prior febrile seizures or the occurrence of a partial seizure were significant predictors of recurrence.Age at first seizure and duration of seizure did not affect recurrence risk in either the idiopathic or remote symptomatic group.A total of 84%of the children were not treated with antiepileptic drugs or were treated for less than 2 weeks.Only 9%were treated for longer than 3 months.Treatment did not affect the risk of recurrence.The results suggest that,even without treatment,the majority of children with a first unprovoked seizure will not experience a recurrence.Children with an idiopathic first seizure and a normal electroencephalogram have a particularly favorable prognosis.
 
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