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We reviewed the clinical features and ictal EEGs in 23 adults with myoclonic status epilepticus(MSE).Anoxic encephalopathy was the most common cause of MSE,occurring in 15 patients;8 developed MSE within 14 hours following the anoxic insult.Metabolic encephalopathies were present in 4 patients,while 2 had degenerative CNS disorders.In 2 patients with generalized epilepsy,MSE developed during a medication change.Five types of EEG patterns were associated with MSE.Generalized periodic complexes (usually spikes,polyspikes,or sharp waves),often with attenuation of background activity between complexes(11 patients)or a burst-suppression pattern(4 patients),were the most common types.Outcome was poor;20 patients died without regaining consciousness,while 1 remains in a vegetative state.The 2 patients with generalized epilepsy,both of whom were conscious during MSE,survived without sequelae. |
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encephalopathy,anoxic myoclonus,epilepsy prognosis status epilepticus status epilepticus,myoclonic
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