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The Willis Lecture:Transient Ischemic Attacks, Scientific Method, and New Realities Stroke 22:99-104, Toole,J.F., 1991 See this aricle in Pubmed Article Abstract First described by Thomas Willis in 1679 and defined in the 1950s, transient ischemic attack is universally agreed to be an episode of focal neurologic deficit in a vascular distribution,sudden in onset and resolving without residual deficit in

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