Neurology Specific Literature Search   
 
[home][thesaurus]
    
Click Here to return To Results

 

Eosinophilia-Myalgia Syndrome, A Clinical Case Series of 21 Patients
Arch Int Med 151:533-537, Philen,R.M.,et al, 1991
See this aricle in Pubmed

Article Abstract
We reviewed 21 cases of eosinophilia-myalgia syndrome to describe the range of clinical findings in these patients.Most patients were women(20[ 95%])and middle-aged(mean,46 years)and had taken the food supplement L- tryptophan(95%).All cases involved eosinophilia(eosinophil count,>/=2.0 x 10 to the 9th power over L)and incapacitating myalgias.Fourteen(88%)of the 16 patients tested had mild liver function abnormalities.Aldolase levels were abnormal in all patients tested.Muscle biopsies were done in five patients;four showed eosinophilic perimyositis,and one had interstitial inflammation.No physical finding was pathognomonic or universal,but muscle tenderness,tachycardia,and rash were the most common signs found during physical examinations.Seven patients were treated with prednisone,and six showed improvement in muscle pain and a decrease in eosinophilia.The cause of this disorder is still unknown.
 
Related Tags
(click to filter results - removes previous filter)

adverse drug reaction
aldolase
arthralgia
dyspnea
enzyme,serum
eosinophilia
eosinophilia-myalgia syndrome
fever
headache
hepatomegaly
liver function enzymes
L-tryptophan
muscle biopsy
muscle pain
muscle tenderness
prognosis
pruritus
rash
respiratory failure
review article
steroid therapy,CNS treatment and complications with
tachycardia
treatment of neurologic disorder
weakness

Click Here to return To Results