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Acute Psychoses Associated with the Use of Ciprofloxacin & Trimethoprim-Sulfamethoxazole
Am J Med 90:528-529, McCue,J.D.&Zandt,J.R., 1991
See this aricle in Pubmed
Article Abstract
Although adverse drug reactions are a well-recognized cause of mental status changes in the elderly,antimicrobials are rarely implicated.Three patients with serious organic brain disease developed paranoid psychosis after therapy with trimethoprim-sulfamethoxazole or ciprofloxacin was begun.One of the patients was accidently rechallenged and again developed a psychotic reaction.The acute psychoses did not improve with moderate doses of major tranquilizers but resolved completely with drug discontinuation.
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adverse drug reaction
antibiotics
antibiotics,neurologic complications with
ciprofloxacin
drug induced neurologic disorders
fluoroquinolones
mental status,abnormal
paranoia
psychosis
psychosis,acute
trimethoprim-sulfamethoxazole
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