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Serial magnetic resonance(MR)imagings of two autopsied patients with Creutzfeldt-Jakob disease(CJD)are presented.Both patients showed a dramatic progression of brain atrophy.The initial MR imagings were, however,interpreted as normal except for localized mild cortical atrophy in one patient.When a normal MR image is obtained in a demented middle- aged or aged patient,CJD may still need to be ruled out:follow up MR imaging may be useful. |
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