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Immunosuppressive Treatment in Multifocal Motor Neuropathy Ann Neurol 30:397-401, Feldman,E.L.,et al, 1991 See this aricle in Pubmed Article Abstract We report the results of immunosuppressive treatments of 13 patients with multifocal motor neuropathy and elevated titers of serum antibodies to the GM1 ganglioside.All patients failed to respond to oral prednisone.There was no clinical response in 4 patients treated with plasma exchange.Nine patients received cyclophosphamide,with clinical improvement and fall in antibody titers in 8.In 3 patients,cyclophosphamide was discontinued with ensuing clinical relapse and rise in the titers of serum anti-GM1 antibodies.These patients provide further evidence for the efficacy of cyclophosphamide therapy in patients with multifocal motor neuropathy.

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(click to filter results - removes previous filter) cyclophosphamide GM1 ganglioside antibodies immunosuppressive agents nerve conduction studies nerve conduction studies,motor neuropathy neuropathy,motor neuropathy,motor,multifocal neuropathy,multifocal neuropathy,peripheral,treatment treatment of neurologic disorder weakness

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