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Two Alien Hand Syndromes Neurol 42:19-24, Feinberg,T.E.,et al, 1992 See this aricle in Pubmed Article Abstract Review of the clinical characteristics and neuroanatomy of 20 reported cases of alien hand syndrome(AHS)and a patient of our own confirm that AHS is actually two distinct syndromes.Frontal AHS occurs in the dominant hand;is associated with reflexive grasping,groping,and compulsive manipulation of tools;and results from damage to the supplementary motor area,anterior cigulate gyrus,and medial prefrontal cortex of the dominant hemisphere and anterior corpus callosum.Callosal AHS is characterized primarily by intermanual conflict and requires only an anterior callosal lesion.The occurrence of frontal AHS in the dominant limb can be explained by an increased tendency for dominant limb exploratory reflexes coupled with release from as asymmetrically distributed predominant nondominant- hemisphere inhibition.Callosal AHS is best explained by hemisphere disconnection manifested during behaviors requiring dominant-hemisphere control.

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(click to filter results - removes previous filter) alien hand syndrome cerebrovascular accident corpus callosum corpus callosum,lesion of frontal lobe,lesion of grasp reflex grasping self-grasping

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