|
|
|
|
In five cases,we found the typical appearance of mitochondrial myopathy, with the presence of numerous RRF.Histochemical and biochemical results confirmed these mitochondrial myopathies,showing miscellaneous deficiencies of mitochondrial respiratory chain enzymes.Persistence of histologic and biochemical abnormalities after steroid treatment in two patients seems to indicate that a subclinical mitochondrial myopathy preceded polymyalgia rheumatica.How a mitochondrial myopathy could induce or facilitate the emergence of a polymyalgia rheumatica remains unknown. |
|