Neurology Specific Literature Search   
 
[home][thesaurus]
    
Click Here to return To Results

 

Invasion of the Central Nervous System by Borrelia Burgdorferi in Acute Disseminated Infection
JAMA 267:1364-1367, Luft,B.J.,et al, 1992
See this aricle in Pubmed

Article Abstract
Eight of the 12 patients(four of six with multiple areas of erythema migrans and four of six with cranial neuritis without erythema migrans)had B burgdorferi-specified DNA in their CSF.Among the 12 patients studied, nine had acute cranial neuritis and six had multiple erythema migrans lesions.Just four of the eight who were found to have spirochetal DNA in their CSF had complaints suggestive of CNS infection.In three of the PCR- positive CSF samples,no other abnormalities were noted.None of 16 samples from controls were positive in the PCR assay.B-burgdorferi can invade the CNS early in the course of infection.Careful consideration should be given to choosing antibiotics that achieve adequate CSF levels in patients with disseminated infection.
 
Related Tags
(click to filter results - removes previous filter)

antibiotics
Borrelia burgdorferi infection
ceftriaxone
central nervous system,infection of
cerebrospinal fluid
cerebrospinal fluid,abnormal
cranial neuropathy
cranial neuropathy,multiple
erythema migrans
Lyme disease
penicillin
polymerase chain reaction
serologic testing
serologic testing of cerebrospinal fluid
skin,lesions in neurologic disorders
spirochete infection
tetracycline
treatment of neurologic disorder

Click Here to return To Results