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Three patients with polymyositis refractory to conventional steroid and immunosuppressive treatment,but responsive to cyclosporin A,are described. In a fourth patient cyclosporin A was used as a first line drug in combination with steroids in the treatment of life-threatening dermatomyositis.Cyclosporin A in the management of polymyositis/ dermatomyositis requires formal assessment of its costs and benefits compared with conventional treatments. |
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