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Over two years,169 cases were identified,and 149 participated in the case- control study.Compared to those who never smoked,the odds ration for current heavy smokers(>20 cigarettes/day)was 11.1(95%confidence interval[ CI]5.0-24.9);for current light smokers(=cigarettes/day),4.1(95%CI,2.3-7. 3);and for former smokers,1.8(95%CI,1.0-3.2).The risk associated with smoking was greatest in the three hours after a cigarette(odds ratio[OR]= 7.0;95%CI,3.7-13.1)and then fell,not reaching the risk in those who had never smoked until more than 10 years had passed since the last cigarette. Heavy alcohol use(>2 drinks a day)was also associated with bleeds(OR=2.2; 95%CI,0.9-5.1,after adjusting for smoking status).These associations were not substantially altered after adjusting for several possible confounding factors,including a history of hypertension.Conclusions:Cigarette smoking and heavy alcohol use are associated with the occurrence of subarachnoid hemorrhage. |
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