|
|
|
|
|
Click Here to return To Results
|
|
|
|
Thirty patients with lesions due to the rupture and repair of an aneurysm of the anterior communicating artery were compared neuropsychologically with 27 patients with ruptures but no lesions and 30 normal control subjects.Patients with combined lesions in the basal forebrain and striatum(n=5),or basal forebrain,striatum,and ventral frontal cortex(n=7), had severe memory deficits,whereas patients with lesions in the basal forebrain(n=7)or the striatum(n=5)alone showed virtually no deficits. Patients with lesions of the basal forebrain and ventral frontal cortex together(n=6)showed mild memory deficits.In contrast to the memory effects,emotional changes were most pronounced in patients with striate lesions alone.Basal forebrain or ventral frontal lesions ameliorated rather than aggravated the emotional effects of striate lesions.It is suggested that the basal forebrain and the striatum form links of different pathways related to mnemonic information processing.Both systems may be able to compensate for a dysfunction of the other,but lesions of both systems together may lead to strong and unrecoverable memory deficits. |
|
(click to filter results - removes previous filter)
aneurysm
aneurysm,anterior communicating
Korsakoff's psychosis
memory,defect of recent
memory,impairment of
subarachnoid hemorrhage
|
Click Here to return To Results
|
|