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Fibromyalgia Syndrome in Patients Infected with Human Immunodeficiency Virus
Am J Med 92:368-374, Simms,R.W.,et al, 1992
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Article Abstract
Thirty-seven of 140 patients with HIV infection had muskuloskeletal symptoms.Three of these 37 patients had arthritis,but none had Reiter's syndrome or psoriatic arthritis.Thirty(81%)of 37 patients had chronic musculoskeletal symptoms(for 3 months or longer).Twenty of 30 patients with chronic musculoskeletal symptoms had polyarthralgia,and of those,15 (75%)were found to have either definite or probable fibromyalgia syndrome. Therefore,fibromyalgia syndrome was found in 41%of HIV-infected patients with musculoskeletal symptoms and in approximately 11%of all HIV-infected patients.Fibromyalgia patients with HIv infection had a longer duration of HIV infection(p=0.01)and more frequently reported past depressed mood(p=0. 001)than HIV-infected patients without fibromyalgia.Compared with 301 patients with fibromyalgia syndrome and no known risk behavior for HIV, known HIV-infected patients with fibromyalgia were more commonly male(p=0. 001)and reported current depressed mood more frequently(p=0.0001). Conclusion:Few patients with arthritis were noted among HIV-infected patients who had intravenous drug use as risk behavior.By comparison, fibromyalgia syndrome appeared to be a common cause of musculoskeletal symptoms in this patient population.
 
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human immunodeficiency virus type 1

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