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Prevalence of Neurosyphilis in Human Immunodeficiency Virus-Infected Patients with Latent Syphilis Am J Med 93:9-12, Holtom,P.D.,et al, 1992 See this aricle in Pubmed Article Abstract A total of 312 patients were screened,of whom 71(22.8%)had reactive serum RPRs and MHA-TPs.Thirty-three of these patients(47%)had diagnostic CSF sampling(26 refused lumbar puncture or were lost to follow-up;12 had had recent therapy for syphilis and thus did not have CSF sampling).Among the 33 patients who had CSF sampling,20(60.6%)had normal CSF profiles(white blood cell count less than 8/mm3;protein less than 0.60 g/L;glucose greater than 2.8 mmol/L)and nonreactive CSF VDRLs.Ten of the 33 patients (30.3%)had abnormal CSF profiles and nonreactive CSF VDRLs,and three of 33 (9.1%)had reactive CSF VDRLs.Conclusions:Asymptomatic neurosyphilis was found in 9.1%of our patient population undergoing CSF sampling,giving a 1. 0%prevalence of CSF VDRL-reactive neurosyphilis in the population we screened.The abnormal CSF findings may have been due to either nonreactive CSF VDRL neurosyphilis,central nervous system infection with HIV,or infection with some unrecognized agent.

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(click to filter results - removes previous filter) asymptomatic cerebrospinal fluid cerebrospinal fluid,abnormal human immunodeficiency virus type 1 lumbar puncture neurosyphilis syphilis,asymptomatic syphilis,diagnosis and treatment Venereal Disease Research Laboratory test

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