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Metastases to the Pituitary-Hypothalamic Axis, An MR Study of 7 Symptomatic Patients Neuroradiology 34:131-134, Schubiger,O.&Haller,D., 1992 See this aricle in Pubmed Article Abstract Seven patients with metastatic tumour in the pituitary-hypothalamic axis were investigated by MRI.The main clinical problems were diabetes insipidus(5 cases)and general pituitary dysfunction(2 cases).No patient had visual or oculomotor symptoms.In 6 of the 7 patients the primary malignant tumour was known,but no patient had symptoms from the primary tumour;1 had symptoms from metastases in locations other than the pituitary gland.In one patient no primary tumour was known.MR detection of a second,clinically silent,5 mm lesion in the posterior cranial fossa initiated the search for primary tumour.MRI showed purely suprasellar tumours in 3 patients and intra-and suprasellar tumours in 4.The latter were dumbbell lesions with only a small bridge of tissue connecting the intra-and suprasellar portions.Six of the 7 suprasellar tumours seemed to be in the infundibular recess of the third ventricle;in 5 the infundibulum was visible as an enhancing linear structure at the postero-inferior border of the tumour.The pituitary fossa was normal in all cases.

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(click to filter results - removes previous filter) diabetes insipidus hypopituitarism MRI MRI,abnormal neoplasm,metastatic to CNS neoplasm,pituitary pituitary pituitary,insufficiency of pituitary,metastasis to suprasellar lesion

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