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At each follow-up assessment,the decreased-risk group had lower scores for distress than before testing(P>0.001).The increased-risk group showed no significant change from base line on any follow-up measure,but over the year of study there were small linear declines(P<0.023)for distress and depression.The no-change group had scores lower than at base line on the index of general well-being at each follow-up(P=0.045).At the 12-month follow-up,both the increased-risk group and the decreased-risk group had lower scores for depression and higher scores for well-being than the no- change group(P=0.049).Predictive testing for Huntington's disease has potential benefits for the psychological health of persons who receive results that indicate either an increase or a decrease in the risk of inheriting the gene for the disease. |
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