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A patient with progressive neurological deterioration characterized by cognitive impairment,myoclonus,Parkinson's syndrome,an abnormal electroencephalogram and fasciculations was considered for brain biopsy for suspected Creutzfeldt-Jakob disease.Complete clinical recovery followed discontinuation of lithium and nortriptyline.Awareness of this unusual drug-induced Creutzfeldt-Jakob like syndrome can avoid costly, invasive and unnecessary investigative procedures. |
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