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Rapid Coma Resolution with Artemether in Malawain Children with Cerebral Malaria Lancet 341:661-662, Taylor,T.E.,et al, 1993 See this aricle in Pubmed Article Abstract Artemisinin compunds clear parasitaemia more rapidly than other drugs do in both mild and severe malaria,but no advantage in clinical efficacy has been shown.We have compared artemether treatment with standard quinine treatment in Malawian children and cerebral malaria.65 unconscious children were randomly allocated to intravenous quinine(n=37)or intramuscular artemeter(n=28)treatment.Two groups were well matched for various prognostic features.Median parasite clearance times were shorter in the artemeter group(28[interquartile range 18-34]vs 40[36-44]h in the quinine gruop,p=0.0002).Coma resilution times were aksi shorter with artemeter than with quinine(8[4-15]vs 14[10-36]h,p=0.01).

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(click to filter results - removes previous filter) artemether coma malaria malaria,cerebral parasitic infection,CNS treatment of neurologic disorder

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