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Reduction in Incidence of Optic Nerve Disease with Annual Ivermectin to Control Onchocerciasis Lancet 341:130-134, 153-1541993., Abiose,A.,et al, 1993 See this aricle in Pubmed Article Abstract The safety and efficacy of ivermectin in the prevention of blindness from onchocerciasis have been established in many studies that have addressed the drug's effects on the from of the eye.We undertook a study with sufficient statistical power to detect an effect on optic nerve disease (OND),probably the main cause of blindness in the disorder.There was evidence that ivermectin reduced the incidence of OND in subjects with mocrofilarial loads above 10 mf/mg but had little effect in those with lower loads.Sustained annual delivery of ivermectin could prevent a substantial proportion of onchocercal blindness in mesoendemic communities.

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(click to filter results - removes previous filter) blindness blindness,prevention of helminthic infection of CNS ivermectin onchocerciasis optic nerve optic nerve,lesion of optic neuropathy parasitic infection,CNS treatment of neurologic disorder visual acuity,decreased visual loss

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