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Cerebral Lymphoma Presenting as a Nonenhancing Lesion on CT/MR Scan
Ann Neurol 33:308-311, DeAngelis,L.M., 1993
See this aricle in Pubmed

Article Abstract
Cerebral lymphoma is usually identified on computed tomogrpahy/megnetic resonance scan as homogeneously contrast-enhancing periventricular msas lesion.We present 10 patients with cerebral lymphoma who had nonenhancing tumors on computed tomographic(2 patients)or magnetic resonance scan(8 patients)either at the time of diagnosis or recurrence.The absence of enhancement caused diagnostic delay in all patients and suggests that tumor resides behind an intact blood-brain barrier,raising important therapeutic implications in the design of chemotherapeutic regiments.
 
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